THE ELUSIVE MALARIA VACCINE: Miracle or Mirage?
by Irwin W. Sherman
2009, 402 pages. Chronicling a 100-year quest, this book tells the fascinating story of the hunt for the still-elusive malaria vaccine. Its clear, engaging style brings to life all the drama of the hunt, celebrating the triumphs and documenting the failures. It captures the controversies, missteps, wars of words, stolen ideas, and clashes of ego as researchers around the world compete to develop the first successful malaria vaccine.
The book is based on the author’s thorough investigation of the scientific literature as well as his first-hand interviews with todays pioneers in malaria vaccine research. As a result, it offers remarkable insights into the keys to a successful malaria vaccine and the obstacles hindering its development.
Malaria is one of humankinds greatest killers, afflicting some 300 to 500 million people. Moreover, malaria infections have begun to spread and surge in places previously free from the disease. With the books easy-to-follow coverage of such topics as immunity, immunology, recombinant DNA, and monoclonal antibodies, readers gain a new understanding of the disease itself, the importance of microbe hunters, and the need for responsible leadership to face the challenges that lie ahead in the battle against malaria. Hardcover; 6-1/4 x 9-1/4″.
Contents: 1. Hunting Microbes; 2. Malaria, the Sickness; 3. The Immunity Alphabet; 4. From Milkmaids to Vaccines;
5. Fundamental Findings; 6. Dreams about Vaccines; 7. Promises, Promises, Promises; 8. Hunting for Protective Blood Stage Antigens; 9. Blocking Transmission; 10. Battling Blood Stages; 11. Of Mice and Men; 12. Informed by the Immune System;
13. Why the Vaccine Remains Elusive
Irwin W. Sherman, Professor Emeritus at the University of California, Riverside, has published more than 150 scholarly ppapers, and has written five books.
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